Line a 15x10x1-inch baking sheet with the saltine crackers. Set aside. Preheat oven to 375°F.
In a small saucepan over medium-high heat, melt butter. Add in sugar and bring to a rolling boil, stirring constantly. Once it begins to boil, remove from heat.
Pour over saltine crackers. Place in a 375°F oven for about 13-15 minutes, until crackers are browned and caramelized.
Remove from oven and using a small spatula, place each piece of toffee onto a sheet of parchment paper on the counter.
Melt white chocolate wafers and spread generously over toffee. Immediately sprinkle with chopped pistachios and dried cranberries. Allow chocolate to set and store in airtight container for up to 7 days.
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