★★★★★

Chicken Tetrazzini Recipe

Chicken Tetrazzini is a creamy, cheesy pasta dish that the whole family will love. Easy to make and freezer friendly, it’s a great casserole to share with friends.

Use up some leftover turkey breast and whip up a dish of this easy, cheesy Turkey Tetrazzini for the holidays!

Chicken tetrazzini scooped onto a white dinner plate with silver fork.

Comfort Food for Dinner

Two of my children have left the nest, and this Chicken Tetrazzini recipe is what they always request when they come home.

It’s delicious comfort food, a great recipe, and easy to make ahead of time too!

This is also one of those recipes I like to keep on hand for when I want to bring a family in need a hearty meal, or a new mom a dinner! It gets rave reviews, and I even made a video tutorial to show you how to make chicken tetrazzini!

This cheesy dish needs to happen in your kitchen. It makes a big 13×9 pan, but you can split it into two dishes (2qt or 8-inch square) and share it with a neighbor or friend in need!

This dish ALWAYS gets people asking for the recipe, and once you try it, you’ll understand why our family loved it!!

FAVORITE PASTA DINNERS: Penne Rosa | Pizza Stuffed Shells

Ingredients you'll need to make chicken tetrazzini, including cooked chicken, pasta, cream of chicken soup and more.

Ingredient Notes

  • Chicken breasts or rotisserie chicken- we love this easy shredded chicken recipe!
  • Cream Soup- Every instinct is going to make you want to sub for something homemade and from scratch, but this is one of those times that comfort food wins, and the canned stuff just tastes better!
  • Unsalted butter
  • Sour cream– or plain greek yogurt
  • Dry white wine– (or chicken broth)
  • Salt and pepper
  • Parmesan cheese
  • Mozzarella cheese
  • Spaghetti noodles – can also use any other pasta of choice.
  • onions, garlic, and mushrooms optional

How to make Chicken Tetrazzini

Step by step photos showing how to make Chicken Tetrazzini.
  • Cook the chicken. You’ll want to start by baking chicken or using leftover turkey, rotisserie chicken, or leftover cooked chicken. If I’m in a hurry, I’ll boil some boneless skinless chicken breasts in a pot of water with salt and pepper to use in this cheesy dish!
  • Cook the pasta. Pick your favorite kind of pasta and cook it until al dente.

What is al dente pasta? It just means that the pasta is still slightly firm. Because you will be baking this dish, you don’t want your pasta too soft and mushy!

  • Combine Ingredients. While you are cooking pasta and chicken, combine the remaining ingredients in a very large bowl. Add your hot pasta and your cooked (diced) chicken to the bowl and mix until blended.
  • Assemble and Bake. Pour into a large 13×9 baking dish (or two smaller pans). Bake covered for about 45 minutes, then remove foil and bake uncovered for an additional 15 minutes, until bubbly and cheese is melted.

Make in Advance: Refrigerate and cover until ready to heat. If cooking from cold, add bake for one hour, then uncovered for 20 minutes. ENJOY.

Chicken tetrazzini baked in a white 13x9 dish and served with a green side salad.

Serving Suggestions

Chicken Tetrazzini is one of those easy dinner recipes that goes great with any green salad or garlic bread!

  • Easy, buttery Beer Bread recipe to serve with dinner! Also great to cube into bite sized pieces and use for dips!
  • This delicious Spinach and Bacon Salad is a breeze to prepare! The sweet dressing with the salty bacon keeps you wanting more!
  • Looking for a fresh bowl of homemade applesauce for dinner tonight? This Instant Pot Applesauce recipe is super quick and easy!
  • Don’t forget to finish the meal with a fresh batch or rice krispie treats!

Recipe FAQs

Can you freeze Chicken Tetrazzini

Yes! Assemble the chicken tetrazzini casserole in a freezer safe dish. When opting to freeze this dinner, I usually choose a foil pan for freezing. Cover with foil and freeze for up to two months.
To serve, thaw in refrigerator overnight, and bake accordingly.

What goes with Chicken Tetrazzini

Serve this delicious pasta dish with Olive Garden breadsticks and Italian salad for the perfect meal.

Can I make tetrazzini without mushrooms?

Absolutely. Leave out the mushrooms or add in extra depending on your taste buds. You can also add in fresh cut broccoli florets!

Can Chicken Tetrazzini be made ahead of time?

Yes. Before baking, cover with foil and refrigerate for up to 24 hours. When ready to bake, remove from fridge and add 10-15 minutes baking time.

Chicken casserole served on a white dinner plate with two small side salads in background.

More Easy Chicken Recipes

Yield: serves 10

Chicken Tetrazzini

Prep Time 15 minutes
Cook Time 1 hour
Total Time 1 hour 15 minutes

Chicken Tetrazzini is a creamy, cheesy pasta dish that the whole family will love. Easy to make and freezer friendly, it's a great casserole to share with friends.

Ingredients

  • 16 ounce thin spaghetti, cooked (or any of your favorite noodles)
  • 2 cups cooked chicken (about 1 pound)
  • ½ cup unsalted butter (plus more for buttering pan)
  • 2 cans cream of chicken soup
  • 2 cups sour cream
  • ½ cup dry white wine
  • 1 teaspoon kosher salt
  • ½ teaspoon ground black pepper
  • 2 Tablespoons parmesan cheese
  • 2 cups shredded mozzarella cheese

Instructions

  1. Combine ½ cup butter, cooked chicken, soup, sour cream, salt, pepper and white wine. Add cooked noodles.
  2. Pour into a buttered 13x9. Sprinkle both cheeses on top.
  3. Bake in a 300 degree oven for 45 minutes, covered with foil. Remove foil and bake uncovered for another 15 minutes.
  4. May be made in advance and refrigerated (before cooking). However, add time if that is the case to heat thoroughly! Enjoy!

Notes

  • Can you freeze Chicken Tetrazzini? Yes! Assemble the chicken tetrazzini casserole in a freezer safe dish. When opting to freeze this dinner, I usually choose a foil pan for freezing. Cover with foil and freeze for up to two months.To serve, thaw in refrigerator overnight, and bake accordingly.
  • Can I make tetrazzini with or without mushrooms? Absolutely. Leave out the mushrooms or add in extra depending on your taste buds. You can also add in fresh cut broccoli florets!
  • Can Chicken Tetrazzini be made ahead of time? Yes. Before baking, cover with foil and refrigerate for up to 24 hours.When ready to bake, remove from fridge and add 10-15 minutes baking time.
  • See blog post for more recipe tips, tricks, and ingredient substitutions.

Nutrition Information:

Yield:

10

Serving Size:

1

Amount Per Serving: Calories: 385Total Fat: 26gSaturated Fat: 14gTrans Fat: 1gUnsaturated Fat: 9gCholesterol: 79mgSodium: 893mgCarbohydrates: 22gFiber: 1gSugar: 3gProtein: 13g

Did you make this recipe?

Please leave a comment on the blog or share a photo on Instagram

Creamy baked Chicken Tetrazzini recipe is the best weeknight dinner recipe your family will love! Easy and delicious.

About Aimee

Aimee is a dessert lover (specifically rice krispie treats), workout enthusiast, self-taught foodie, and recipe creator.

Learn more about Aimee.

Affiliate Disclosure:**There may be affiliate links in this post! By clicking on them, or purchasing recommended items I may receive a small compensation. However, I only recommend products I love! Thank you for supporting Shugary Sweets! See my disclosure policy for more info**

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Posted on June 24, 2020

Comments & Reviews

  1. I think this would easily become a favorite dish in my house too. I’m putting into my meal planning menu for later this month.

  2. This looks so creamy and delicious! I love that it can be made ahead of time – that’s always a bonus in my book!

  3. This recipe reminds me of when I was a kid, because my mom always used to make this for us! I’m going to have to make it for my kids and see what they think.

  4. I love cooking up a bunch of chicken and freezing it to use in easy meals like this. It looks so creamy and delicious, I think my entire family will love it!

  5. I made this tonight. I did make a few adjustments to the recipe. I added broccoli and used cream of chicken and mushroom soup instead of just cream of chicken. We thought it tasted a lot like tuna noodle casserole. My husband liked it but I wasn’t a fan. If you like tuna noodle casserole you will love this!

  6. Hi!!! My neighbor made this and loved it!
    So,I’m making this tonight.. super excited!
    Can I substitute the sour cream with Yogurt? Or would you suggest using Butter milk? (My husband hates sour cream, even tho I LOVE IT. Lol)

    Thanks!!

  7. Ive loved this recipe for several years, usually I add halved cherry tomatoes and chopped up artichoke hearts. Mmmm soo amazing.

    I just served this at my wedding, we premade 11 triple batches and froze them. Put them in the fridge a few days before and had friends bake them the day of. It was an econimical way to feed 300 people and we did all of the cooking in one day! Thank You so much for tgis recipe!

  8. Is there an alternative for Cream of Chicken Soup ? I’m allergic to MSG…. Have yet to find a Cream of Chicken Soup that doesn’t have MSG?

    Thank you,

  9. I needed a casserole that I could make ahead to take to my parents. This is delicious, my mom really liked it, she has Crohn’s so I have to be careful with recipes. I didn’t use the wine and I didn’t use much salt since I was using the canned soup but I did throw a little parm in with the soup and sour cream and I took the lazy way out and purchased a rotisserie chicken and cleaned it to use. I will definitely make this again.

  10. FYI for those asking if they can substitute wine in recipe…. you can substitute apple cider (sparkling or otherwise) or white grape juice.  I have used both (most generally I buy the 4 packs of mini apple cider bottles to keep in my fridge for when wine pops up in a recipe).  And my food always turns out just as good and in many times, better.  I also added sautéed onions inside the casserole.  I used cheddar and parmesean bcuz I didn’t have the cheese called for in the recipe.   The last 10 minutes I topped with homemade bread crumbs and French’s crispy onions….Hubby loved this dish!  Thx for the recipe!

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